PDB entry 5ayt
View 5ayt on RCSB PDB site
Description: Crystal structure of transthyretin in complex with L6
Class: transport protein/inhibitor
Keywords: Amyloidogenic protein, Inhibitor, Stabilizer, Drug discovery, TRANSPORT PROTEIN-INHIBITOR complex
Deposited on
2015-09-03, released
2016-01-20
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-02-26, with a file datestamp of
2020-02-21.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5ayta_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5aytb_ - Heterogens: L6Y, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5aytA (A:)
mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
avhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
ehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5aytA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5aytB (B:)
mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
avhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
ehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5aytB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn