PDB entry 5ayt

View 5ayt on RCSB PDB site
Description: Crystal structure of transthyretin in complex with L6
Class: transport protein/inhibitor
Keywords: Amyloidogenic protein, Inhibitor, Stabilizer, Drug discovery, TRANSPORT PROTEIN-INHIBITOR complex
Deposited on 2015-09-03, released 2016-01-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-01-20, with a file datestamp of 2016-01-15.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ayta_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5aytb_
  • Heterogens: L6Y, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5aytA (A:)
    mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
    avhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
    ehaevvftandsgprrytiaallspysysttavvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >5aytA (A:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5aytB (B:)
    mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
    avhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
    ehaevvftandsgprrytiaallspysysttavvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >5aytB (B:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn