PDB entry 5avw

View 5avw on RCSB PDB site
Description: Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 16.5 min
Class: hydrolase/transport protein
Keywords: membrane protein, ion pump, ATPase, k+ binding, haloacid dehydrogenease superfamily, phosphate analogue, ATP-binding, hydrolase, ion transport, nucleotide-binding, phosphoprotein, hydrolase-transport protein complex, kinetics
Deposited on 2015-07-01, released 2015-09-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-09-02, with a file datestamp of 2015-08-28.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Na, K-ATPase alpha subunit
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5avwa1, d5avwa2, d5avwa3, d5avwa4
  • Chain 'B':
    Compound: Na+,K+-ATPase beta subunit
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5avwb1, d5avwb2
  • Chain 'G':
    Compound: Phospholemman-like protein
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5avwg_
  • Heterogens: MF4, MG, TL, K, CLR, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5avwA (A:)
mgkgtasdkyepaatsenatkskkkgkkdkidkkrdldelkkevsmddhklsldelhnky
gtdltrgltnarakeilardgpnsltpppttpewikfcrqlfggfsillwigailcflay
giqaatedepandnlylgvvlstvvivtgcfsyyqeakssrimdsfknmvpqqalvirdg
ekstinaefvvagdlvevkggdripadlriisahgckvdnssltgesepqtrspefssen
pletrniaffstncvegtargvvvytgdrtvmgriatlasglevgrtpiaieiehfihii
tgvavflgvsffilslilgyswleavifligiivanvpegllatvtvcltltakrmarkn
clvknleavetlgststicsdktgtltqnrmtvahmwfdnqiheadttenqsgaafdkts
atwsalsriaalcnravfqagqdnvpilkrsvagdasesallkcielccgsvqgmrdrnp
kiveipfnstnkyqlsihenekssesryllvmkgaperildrcstillngaeeplkedmk
eafqnaylelgglgervlgfchfalpedkynegypfdadepnfpttdlcfvglmamidpp
raavpdavgkcrsagikvimvtgdhpitakaiakgvgiisegnetiediaarlnipigqv
nprdakacvvhgsdlkdlstevlddilhyhteivfartspqqkliivegcqrqgaivavt
gdgvndspalkkadigvamgisgsdvskqaadmillddnfasivtgveegrlifdnlkks
iaytltsnipeitpflvfiignvplplgtvtilcidlgtdmvpaislayeqaesdimkrq
prnpktdklvnerlismaygqigmiqalggffsyfvilaengflpmdligkrvrwddrwi
sdvedsfgqqwtyeqrkiveftchtsffisivvvqwadliicktrrnsifqqgmknkili
fglfeetalaaflsycpgtdvalrmyplkpswwfcafpysliiflydemrrfiirrspgg
wveqetyy

    Sequence, based on observed residues (ATOM records): (download) 
    >5avwA (A:)
ldelkkevsmddhklsldelhnkygtdltrgltnarakeilardgpnsltpppttpewik
fcrqlfggfsillwigailcflaygiqaatedepandnlylgvvlstvvivtgcfsyyqe
akssrimdsfknmvpqqalvirdgekstinaefvvagdlvevkggdripadlriisahgc
kvdnssltgesepqtrspefssenpletrniaffstncvegtargvvvytgdrtvmgria
tlasglevgrtpiaieiehfihiitgvavflgvsffilslilgyswleavifligiivan
vpegllatvtvcltltakrmarknclvknleavetlgststicsdktgtltqnrmtvahm
wfdnqiheadttenqsgaafdktsatwsalsriaalcnravfqagqdnvpilkrsvagda
sesallkcielccgsvqgmrdrnpkiveipfnstnkyqlsihenekssesryllvmkgap
erildrcstillngaeeplkedmkeafqnaylelgglgervlgfchfalpedkynegypf
dadepnfpttdlcfvglmamidppraavpdavgkcrsagikvimvtgdhpitakaiakgv
giisegnetiediaarlnipigqvnprdakacvvhgsdlkdlstevlddilhyhteivfa
rtspqqkliivegcqrqgaivavtgdgvndspalkkadigvamgisgsdvskqaadmill
ddnfasivtgveegrlifdnlkksiaytltsnipeitpflvfiignvplplgtvtilcid
lgtdmvpaislayeqaesdimkrqprnpktdklvnerlismaygqigmiqalggffsyfv
ilaengflpmdligkrvrwddrwisdvedsfgqqwtyeqrkiveftchtsffisivvvqw
adliicktrrnsifqqgmknkilifglfeetalaaflsycpgtdvalrmyplkpswwfca
fpysliiflydemrrfiirrspggwveqetyy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5avwB (B:)
margksketdggwkkflwdsekkeflgrtgsswfkiflfylifygclagifigtiqvlll
tlsdfepkyqdrvappglshapyaikteisfsisnpksyesfvksmhklmdlynessqag
nspfedcsdtpadyikrgdlddsqgqkkacrfsrmwlkncsglddttygyaegkpcvvak
lnriigfypkplknttdlpeelqanynqyvlplrcaakreedrekigsieyfglggyagf
plqyypyygkrlqkkylqpllaiqftnltqnmelrieckvygenidysekdrfrgrfevk
ievks

    Sequence, based on observed residues (ATOM records): (download) 
    >5avwB (B:)
flgrtgsswfkiflfylifygclagifigtiqvllltlsdfepkyqdrvappglshapya
ikteisfsisnpksyesfvksmhklmdlynessqagnspfedcsdtpadyikrgdlddsq
gqkkacrfsrmwlkncgyaegkpcvvaklnriigfypkplknttdlpeelqanynqyvlp
lrcaarekigsieyfglggyagfplqyypyygkrlqkkylqpllaiqftnltqnmelrie
ckvygenidysekdrfrgrfevkievks

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5avwG (G:)
mdpegpdnderftydyyrlrvvglivaavlcvigiiillagkcrckfnqnkrtrsnsgta
taqhllqpgeatec

    Sequence, based on observed residues (ATOM records): (download) 
    >5avwG (G:)
egpdnderftydyyrlrvvglivaavlcvigiiillagk