PDB entry 5ar0

View 5ar0 on RCSB PDB site
Description: HSP72 with adenosine-derived inhibitor
Class: chaperone
Keywords: heat shock protein, hsp70, hsp72, ATPase, chaperone, adenosine, inhibitor
Deposited on 2015-09-22, released 2016-05-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-06-08, with a file datestamp of 2016-06-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: heat shock 70 kda protein 1a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DMV8 (Start-384)
      • expression tag (385-387)
    Domains in SCOPe 2.07: d5ar0a1, d5ar0a2, d5ar0a3
  • Heterogens: GB8, GOL, DMS, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ar0A (A:)
gplgsmakaaaigidlgttyscvgvfqhgkveiiandqgnrttpsyvaftdterligdaa
knqvalnpqntvfdakrligrkfgdpvvqsdmkhwpfqvindgdkpkvqvsykgetkafy
peeissmvltkmkeiaeaylgypvtnavitvpayfndsqrqatkdagviaglnvlriine
ptaaaiaygldrtgkgernvlifdlgggtfdvsiltiddgifevkatagdthlggedfdn
rlvnhfveefkrkhkkdisqnkravrrlrtacerakrtlssstqasleidslfegidfyt
sitrarfeelcsdlfrstlepvekalrdakldkaqihdlvlvggstripkvqkllqdffn
grdlnksinpdeavaygaavqaailikstraaas

    Sequence, based on observed residues (ATOM records): (download) 
    >5ar0A (A:)
kaaaigidlgttyscvgvfqkveiiandqgnrttpsyvaftdterligdaaknqvalnpq
ntvfdakrligrkfgdpvvqsdmkhwpfqvindgdkpkvqvsykgetkafypeeissmvl
tkmkeiaeaylgypvtnavitvpayfndsqrqatkdagviaglnvlriineptaaaiayg
ldrtgkgernvlifdlgggtfdvsiltiddgifevkatagdthlggedfdnrlvnhfvee
fkrkhkkdisqnkravrrlrtacerakrtlssstqasleidslfegidfytsitrarfee
lcsdlfrstlepvekalrdakldkaqihdlvlvggstripkvqkllqdffngrdlnksin
pdeavaygaavqaailiks