PDB entry 5aqk

View 5aqk on RCSB PDB site
Description: Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
Class: chaperone
Keywords: heat shock protein, hsp70, hsp72, hsc70, ATPase, bag1, chaperone, fragment
Deposited on 2015-09-22, released 2016-10-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock cognate 71 kDa protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5aqka1, d5aqka2
  • Chain 'B':
    Compound: BAG family molecular chaperone regulator 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99933 (5-End)
      • expression tag (4)
  • Heterogens: GDP, GOL, TRS, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5aqkA (A:)
gplgsmskgpavgidlgttyscvgvfqhgkveiiandqgnrttpsyvaftdterligdaa
knqvamnptntvfdakrligrrfddavvqsdmkhwpfmvvndagrpkvqveykgetksfy
peevssmvltkmkeiaeaylgktvtnavvtvpayfndsqrqatkdagtiaglnvlriine
ptaaaiaygldkkvgaernvlifdlgggtfdvsiltiedgifevkstagdthlggedfdn
rmvnhfiaefkrkhkkdisenkravrrlrtacerakrtlssstqasieidslyegidfyt
sitrarfeelnadlfrgtldpvekalrdakldksqihdivlvggstripkiqkllqdffn
gkelnksinpdeavaygaavqaails

    Sequence, based on observed residues (ATOM records): (download) 
    >5aqkA (A:)
gpavgidlgttyscvgvfqhgkveiiandqgnrttpsyvaftdterligdaaknqvamnp
tntvfdakrligrrfddavvqsdmkhwpfmvvndagrpkvqveykgetksfypeevssmv
ltkmkeiaeaylgktvtnavvtvpayfndsqrqatkdagtiaglnvlriineptaaaiay
gldkkvgaernvlifdlgggtfdvsiltiedgifevkstagdthlggedfdnrmvnhfia
efkrkhkkdisenkravrrlrtacerakrtlssstqasieidslyegidfytsitrarfe
elnadlfrgtldpvekalrdakldksqihdivlvggstripkiqkllqdffngkelnksi
npdeavaygaavqaails

  • Chain 'B':
    No sequence available.