PDB entry 5apj

View 5apj on RCSB PDB site
Description: Ligand complex of RORg LBD
Class: transcription
Keywords: transcription, rorg ligand, rorg agonist, structure-based design
Deposited on 2015-09-16, released 2015-11-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-02-03, with a file datestamp of 2016-01-29.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor ROR-gamma
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51449 (21-263)
      • expression tag (14-20)
    Domains in SCOPe 2.07: d5apja1, d5apja2
  • Chain 'C':
    Compound: nuclear receptor coactivator 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 76E, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5apjA (A:)
hnhnhnhnhnhnggenlyfqgaslteiehlvqsvcksyretcqlrledllrqrsnifsre
evtgyqrksmwemwercahhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlv
rmcraynadnrtvffegkyggmelfralgcselissifdfshslsalhfsedeialytal
vlinahrpglqekrkveqlqynlelafhhhlckthrqsilaklppkgklrslcsqhverl
qifqhlhpivvqaafpplykelfsgg

    Sequence, based on observed residues (ATOM records): (download) 
    >5apjA (A:)
enlyfqgaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemw
ercahhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvf
fegkyggmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekr
kveqlqynlelafhhhlckthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaa
fpplykelfs

  • Chain 'C':
    No sequence available.