PDB entry 5aks
View 5aks on RCSB PDB site
Description: Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-3-O- glucuronide
Class: transport protein
Keywords: transport protein, amyloid, fibrillogenesis, fibrillogenesis inhibitors, polyphenols, polyphenol metabolites, transthyretin, negative cooperativity
Deposited on
2015-03-05, released
2015-10-21
The last revision prior to the SCOPe 2.06 freeze date was dated
2016-01-13, with a file datestamp of
2016-01-08.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.62
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d5aksa_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d5aksb_ - Heterogens: SO4, R3X, DMS, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5aksA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5aksA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5aksB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5aksB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn