PDB entry 5acv

View 5acv on RCSB PDB site
Description: VIM-2-OX, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening
Class: hydrolase
Keywords: hydrolase
Deposited on 2015-08-18, released 2015-11-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: PSEUDOMONAS AERUGINOSA [TaxId:287]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5acva_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: PSEUDOMONAS AERUGINOSA [TaxId:287]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5acvb_
  • Heterogens: OH, ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5acvA (A:)
mfkllskllvyltasimaiasplafsvdssgeyptvseipvgevrlyqiadgvwshiatq
sfdgavypsnglivrdgdelllidtawgakntaallaeiekqiglpvtravsthfhddrv
ggvdvlraagvatyaspstrrlaevegneipthsleglsssgdavrfgpvelfypgaahs
tdnlvvyvpsasvlyggcaiyelsrtsagnvadadlaewptsieriqqhypeaqfvipgh
glpggldllkhttnvvkahtnrsvve

    Sequence, based on observed residues (ATOM records): (download) 
    >5acvA (A:)
geyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgak
ntaallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegnei
pthsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagn
vadadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5acvB (B:)
mfkllskllvyltasimaiasplafsvdssgeyptvseipvgevrlyqiadgvwshiatq
sfdgavypsnglivrdgdelllidtawgakntaallaeiekqiglpvtravsthfhddrv
ggvdvlraagvatyaspstrrlaevegneipthsleglsssgdavrfgpvelfypgaahs
tdnlvvyvpsasvlyggcaiyelsrtsagnvadadlaewptsieriqqhypeaqfvipgh
glpggldllkhttnvvkahtnrsvve

    Sequence, based on observed residues (ATOM records): (download) 
    >5acvB (B:)
geyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgak
ntaallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegnei
pthsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagn
vadadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrs