PDB entry 5acs

View 5acs on RCSB PDB site
Description: Y233A-Investigation of the impact from residues W228 and Y233 in the metallo-beta-lactamase GIM-1
Class: hydrolase
Keywords: hydrolase, metallo-beta-lactamase, gim-1, carbapenemase, enzyme kinetics, mic
Deposited on 2015-08-17, released 2015-12-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-12-23, with a file datestamp of 2015-12-18.
Experiment type: XRAY
Resolution: 1.46 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gim-1 protein
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q704V1
      • engineered mutation (186)
    Domains in SCOPe 2.06: d5acsa_
  • Chain 'B':
    Compound: gim-1 protein
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q704V1
      • engineered mutation (186)
    Domains in SCOPe 2.06: d5acsb_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5acsA (A:)
    mknvlvflillvalpalaqghkplevikiedgvylhtsfkniegyglvdsnglvvldnnq
    ayiidtpwseedtklllswatdrgyqvmasisthshedrtagikllnsksiptytseltk
    kllaregkpvpthyfkddeftlgnglielyypgaghtednivawlpkskilfggclvrsh
    eweglgavgdasisswadsiknivskkypiqmvvpghgkvgssdildhtidlaesasnkl
    mqptaeasad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5acsA (A:)
    kplevikiedgvylhtsfkniegyglvdsnglvvldnnqayiidtpwseedtklllswat
    drgyqvmasisthshedrtagikllnsksiptytseltkkllaregkpvpthyfkddeft
    lgnglielyypgaghtednivawlpkskilfggclvrsheweglgavgdasisswadsik
    nivskkypiqmvvpghgkvgssdildhtidlaesasnk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5acsB (B:)
    mknvlvflillvalpalaqghkplevikiedgvylhtsfkniegyglvdsnglvvldnnq
    ayiidtpwseedtklllswatdrgyqvmasisthshedrtagikllnsksiptytseltk
    kllaregkpvpthyfkddeftlgnglielyypgaghtednivawlpkskilfggclvrsh
    eweglgavgdasisswadsiknivskkypiqmvvpghgkvgssdildhtidlaesasnkl
    mqptaeasad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5acsB (B:)
    kplevikiedgvylhtsfkniegyglvdsnglvvldnnqayiidtpwseedtklllswat
    drgyqvmasisthshedrtagikllnsksiptytseltkkllaregkpvpthyfkddeft
    lgnglielyypgaghtednivawlpkskilfggclvrsheweglgavgdasisswadsik
    nivskkypiqmvvpghgkvgssdildhtidlaesasn