PDB entry 5acq

View 5acq on RCSB PDB site
Description: W228A-Investigation of the impact from residues W228 and Y233 in the metallo-beta-lactamase GIM-1
Class: hydrolase
Keywords: hydrolase, metallo-beta-lactamase, gim-1, carbapenemase, enzyme kinetics, mic
Deposited on 2015-08-17, released 2015-12-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-12-23, with a file datestamp of 2015-12-18.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q704V1
      • engineered mutation (181)
    Domains in SCOPe 2.06: d5acqa_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q704V1
      • engineered mutation (181)
    Domains in SCOPe 2.06: d5acqb_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5acqA (A:)
mknvlvflillvalpalaqghkplevikiedgvylhtsfkniegyglvdsnglvvldnnq
ayiidtpwseedtklllswatdrgyqvmasisthshedrtagikllnsksiptytseltk
kllaregkpvpthyfkddeftlgnglielyypgaghtednivawlpkskilfggclvrsh
eaeglgyvgdasisswadsiknivskkypiqmvvpghgkvgssdildhtidlaesasnkl
mqptaeasad

    Sequence, based on observed residues (ATOM records): (download) 
    >5acqA (A:)
hkplevikiedgvylhtsfkniegyglvdsnglvvldnnqayiidtpwseedtklllswa
tdrgyqvmasisthshedrtagikllnsksiptytseltkkllaregkpvpthyfkddef
tlgnglielyypgaghtednivawlpkskilfggclvrsheaeglgyvgdasisswadsi
knivskkypiqmvvpghgkvgssdildhtidlaesasn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5acqB (B:)
mknvlvflillvalpalaqghkplevikiedgvylhtsfkniegyglvdsnglvvldnnq
ayiidtpwseedtklllswatdrgyqvmasisthshedrtagikllnsksiptytseltk
kllaregkpvpthyfkddeftlgnglielyypgaghtednivawlpkskilfggclvrsh
eaeglgyvgdasisswadsiknivskkypiqmvvpghgkvgssdildhtidlaesasnkl
mqptaeasad

    Sequence, based on observed residues (ATOM records): (download) 
    >5acqB (B:)
kplevikiedgvylhtsfkniegyglvdsnglvvldnnqayiidtpwseedtklllswat
drgyqvmasisthshedrtagikllnsksiptytseltkkllaregkpvpthyfkddeft
lgnglielyypgaghtednivawlpkskilfggclvrsheaeglgyvgdasisswadsik
nivskkypiqmvvpghgkvgssdildhtidlaesasn