PDB entry 5acp

View 5acp on RCSB PDB site
Description: W228R-Investigation of the impact from residues W228 and Y233 in the metallo-beta-lactamase GIM-1
Class: hydrolase
Keywords: hydrolase, metallo-beta-lactamase, gim-1, carbapenemase, enzyme kinetics, mic
Deposited on 2015-08-17, released 2015-12-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-12-23, with a file datestamp of 2015-12-18.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gim-1 protein
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q704V1
      • engineered mutation (181)
    Domains in SCOPe 2.06: d5acpa_
  • Chain 'B':
    Compound: gim-1 protein
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q704V1
      • engineered mutation (181)
    Domains in SCOPe 2.06: d5acpb_
  • Heterogens: ZN, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5acpA (A:)
    mknvlvflillvalpalaqghkplevikiedgvylhtsfkniegyglvdsnglvvldnnq
    ayiidtpwseedtklllswatdrgyqvmasisthshedrtagikllnsksiptytseltk
    kllaregkpvpthyfkddeftlgnglielyypgaghtednivawlpkskilfggclvrsh
    ereglgyvgdasisswadsiknivskkypiqmvvpghgkvgssdildhtidlaesasnkl
    mqptaeasad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5acpA (A:)
    ghkplevikiedgvylhtsfkniegyglvdsnglvvldnnqayiidtpwseedtklllsw
    atdrgyqvmasisthshedrtagikllnsksiptytseltkkllaregkpvpthyfkdde
    ftlgnglielyypgaghtednivawlpkskilfggclvrshereglgyvgdasisswads
    iknivskkypiqmvvpghgkvgssdildhtidlaesasn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5acpB (B:)
    mknvlvflillvalpalaqghkplevikiedgvylhtsfkniegyglvdsnglvvldnnq
    ayiidtpwseedtklllswatdrgyqvmasisthshedrtagikllnsksiptytseltk
    kllaregkpvpthyfkddeftlgnglielyypgaghtednivawlpkskilfggclvrsh
    ereglgyvgdasisswadsiknivskkypiqmvvpghgkvgssdildhtidlaesasnkl
    mqptaeasad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5acpB (B:)
    kplevikiedgvylhtsfkniegyglvdsnglvvldnnqayiidtpwseedtklllswat
    drgyqvmasisthshedrtagikllnsksiptytseltkkllaregkpvpthyfkddeft
    lgnglielyypgaghtednivawlpkskilfggclvrshereglgyvgdasisswadsik
    nivskkypiqmvvpghgkvgssdildhtidlaesasn