PDB entry 5abw

View 5abw on RCSB PDB site
Description: Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases
Class: hydrolase
Keywords: trypsin family fold, protease, hydrolase, hydrolase-inhibitor complex
Deposited on 2015-08-10, released 2015-08-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-03-22, with a file datestamp of 2017-03-17.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil elastase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5abwa_
  • Heterogens: WQQ, NAG, FUC, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5abwA (A:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
    glihgiasfvrggcasglypdafapvaqfvnwidsiiq
    

    Sequence, based on observed residues (ATOM records): (download)
    >5abwA (A:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllggiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcngli
    hgiasfvrggcasglypdafapvaqfvnwidsiiq