PDB entry 5a8y

View 5a8y on RCSB PDB site
Description: Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor
Class: hydrolase
Keywords: trypsin family fold, protease, hydrolase, hydrolase-inhibitor complex
Deposited on 2015-07-17, released 2016-08-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-09-21, with a file datestamp of 2016-09-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil elastase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5a8ya_
  • Heterogens: NAG, VBM, MES, MLI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5a8yA (A:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
    glihgiasfvrggcasglypdafapvaqfvnwidsiiq
    

    Sequence, based on observed residues (ATOM records): (download)
    >5a8yA (A:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllgrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcngl
    ihgiasfvrggcasglypdafapvaqfvnwidsiiq