PDB entry 5a5s
View 5a5s on RCSB PDB site
Description: NN-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-5-methoxypyridin-3-yl-3- methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one
Class: hydrolase
Keywords: hydrolase, inhibitor, histone, epigenetic reader, bromodomain, brd4, bromodomain containing protein 4, antagonist
Deposited on
2015-06-20, released
2015-07-22
The last revision prior to the SCOPe 2.07 freeze date was dated
2015-08-05, with a file datestamp of
2015-07-31.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: N/A
AEROSPACI score: 0.56
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot O60885 (2-126)
- expression tag (0-1)
- conflict (36)
Domains in SCOPe 2.07: d5a5sa1, d5a5sa2 - Heterogens: EDO, NP8, HOH