PDB entry 5a0c

View 5a0c on RCSB PDB site
Description: Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor
Class: hydrolase
Keywords: trypsin family fold, protease, hydrolase, hydrolase- inhibitor complex
Deposited on 2015-04-17, released 2015-08-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-07-05, with a file datestamp of 2017-06-30.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutrophil elastase
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5a0ca_
  • Chain 'B':
    Compound: Neutrophil elastase
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5a0cb_
  • Heterogens: NAG, FUC, JJV, MES, XPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5a0cA (A:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
    glihgiasfvrggcasglypdafapvaqfvnwidsiiq
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5a0cB (B:)
    ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
    srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
    qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
    glihgiasfvrggcasglypdafapvaqfvnwidsiiq