PDB entry 4zzy

View 4zzy on RCSB PDB site
Description: Structure of human PARP2 catalytic domain bound to an isoindolinone inhibitor
Class: transferase
Keywords: transferase
Deposited on 2015-04-15, released 2015-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-09-23, with a file datestamp of 2015-09-18.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly [ADP-ribose] polymerase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4zzya1, d4zzya2
  • Heterogens: D7N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4zzyA (A:)
gpslksplkpesqldlrvqeliklicnvqameemmmemkyntkkaplgkltvaqikagyq
slkkiedciragqhgralmeacnefytriphdfglrtpplirtqkelsekiqllealgdi
eiaiklvktelqspehpldqhyrnlhcalrpldhesyefkvisqylqsthapthsdytmt
lldlfevekdgekeafredlhnrmllwhgsrmsnwvgilshglriappeapitgymfgkg
iyfadmssksanycfasrlkntgllllsevalgqcnelleanpkaegllqgkhstkglgk
mapssahfvtlngstvplgpasdtgilnpdgytlnyneyivynpnqvrmryllkvqfnfl
qlw

    Sequence, based on observed residues (ATOM records): (download) 
    >4zzyA (A:)
esqldlrvqeliklicnvqameemmmemkyntkkaplgkltvaqikagyqslkkiedcir
agqhgralmeacnefytriphdfglrtpplirtqkelsekiqllealgdieiaiklvkte
lqspehpldqhyrnlhcalrpldhesyefkvisqylqsthapthsdytmtlldlfevekd
gekeafredlhnrmllwhgsrmsnwvgilshglriappeapitgymfgkgiyfadmssks
anycfasrlkntgllllsevalgqcnelleanpkaegllqgkhstkglgkmapssahfvt
lngstvplgpasdtgilngytlnyneyivynpnqvrmryllkvqfnflqlw