PDB entry 4zz3
View 4zz3 on RCSB PDB site
Description: Human GAR transformylase in complex with GAR and pemetrexed
Class: transferase/transferase inhibitor
Keywords: gar transformylase, antifolate, transferase-transferase inhibitor complex
Deposited on
2015-05-22, released
2015-12-16
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-12-16, with a file datestamp of
2015-12-11.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Trifunctional purine biosynthetic protein adenosine-3
Species: Homo sapiens [TaxId:9606]
Gene: GART, PGFT, PRGS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4zz3a_ - Heterogens: 4DW, GAR, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4zz3A (A:)
marvavlisgtgsnlqalidstrepnssaqidivisnkaavagldkaeragiptrvinhk
lyknrvefdsaidlvleefsidivclagfmrilsgpfvqkwngkmlnihpsllpsfkgsn
aheqaletgvtvtgctvhfvaedvdagqiilqeavpvkrgdtvatlservklaehkifpa
alqlvasgtvqlgengkicwvkeehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4zz3A (A:)
arvavlisgtgsnlqalidstrepnssaqidivisnkaavagldkaeragiptrvinhkl
yknrvefdsaidlvleefsidivclagfmrilsgpfvqkwngkmlnihpsllpsfkgsna
heqaletgvtvtgctvhfvaedvdagqiilqeavpvkrgdtvatlservklaehkifpaa
lqlvasgtvqlgengkicwv