PDB entry 4zz2
View 4zz2 on RCSB PDB site
Description: human gar transformylase in complex with gar and (s)-2-({5-[3-(2-amino-4-oxo-4,7-dihydro-3h-pyrrolo[2,3-d]pyrimidin-6-yl)-propyl]-thiophene-3-carbonyl}-amino)-pentanedioic acid
Class: transferase/transferase inhibitor
Keywords: gar transformylase, antifolate, TRANSFERASE-TRANSFERASE INHIBITOR complex, Structural Genomics
Deposited on
2015-05-22, released
2015-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-12-04, with a file datestamp of
2019-11-29.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Trifunctional purine biosynthetic protein adenosine-3
Species: Homo sapiens [TaxId:9606]
Gene: GART, PGFT, PRGS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4zz2a_ - Heterogens: GAR, 3YG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4zz2A (A:)
marvavlisgtgsnlqalidstrepnssaqidivisnkaavagldkaeragiptrvinhk
lyknrvefdsaidlvleefsidivclagfmrilsgpfvqkwngkmlnihpsllpsfkgsn
aheqaletgvtvtgctvhfvaedvdagqiilqeavpvkrgdtvatlservklaehkifpa
alqlvasgtvqlgengkicwvkeehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4zz2A (A:)
arvavlisgtgsnlqalidstrepnssaqidivisnkaavagldkaeragiptrvinhkl
yknrvefdsaidlvleefsidivclagfmrilsgpfvqkwngkmlnihpsllpsfkgsna
heqaletgvtvtgctvhfvaedvdagqiilqeavpvkrgdtvatlservklaehkifpaa
lqlvasgtvqlgengkicwv