PDB entry 4zy6

View 4zy6 on RCSB PDB site
Description: Crystal structure of P21-activated kinase 1 in complex with an inhibitor compound 29
Class: transferase/transferase inhibitor
Keywords: PAK1, Kinase, Inhibitor, Complex
Deposited on 2015-05-21, released 2015-07-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-07-01, with a file datestamp of 2015-06-26.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PAK 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13153
      • engineered mutation (141)
    Domains in SCOPe 2.05: d4zy6a_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase PAK 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13153
      • engineered mutation (141)
    Domains in SCOPe 2.05: d4zy6b_
  • Heterogens: 4T6, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4zy6A (A:)
gsdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqmnlqqqp
kkeliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqia
avcreclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgt
pywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnp
eklsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeatknnhgn
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4zy6A (A:)
eeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqpkkeliinei
lvmrenknpnivnyldsylvelwvvmeylaggsltdvvtetcmdegqiaavcreclqale
flhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpywmapevvtr
kaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdfl
nrclemdvekrgsakellqhqflkiakplssltpliaaakeatk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4zy6B (B:)
gsdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqmnlqqqp
kkeliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqia
avcreclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgt
pywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnp
eklsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeatknnhgn
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4zy6B (B:)
eklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqmnlqqqpkkeliin
eilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavcrecl
qaleflhsnqvihrniksdnillgmdgsvkltdfgfskrstmvgtpywmapevvtrkayg
pkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdflnrcl
emdvekrgsakellqhqflkiakplssltpliaaakeatk