PDB entry 4zy4

View 4zy4 on RCSB PDB site
Description: Crystal structure of P21 activated kinase 1 in complex with an inhibitor compound 4
Class: transferase/transferase inhibitor
Keywords: kinase, Inhibitor, Complex
Deposited on 2015-05-21, released 2015-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-07-15, with a file datestamp of 2015-07-10.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PAK 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13153 (1-End)
      • engineered mutation (141)
    Domains in SCOPe 2.08: d4zy4a_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase PAK 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13153 (1-End)
      • engineered mutation (141)
    Domains in SCOPe 2.08: d4zy4b_
  • Heterogens: 4T3, SO4, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4zy4A (A:)
gsdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqmnlqqqp
kkeliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqia
avcreclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgt
pywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnp
eklsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeatknnhgn
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4zy4A (A:)
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqqpkkelii
neilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavcrec
lqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpywmap
evvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsai
frdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeat

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4zy4B (B:)
gsdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqmnlqqqp
kkeliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqia
avcreclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgt
pywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnp
eklsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeatknnhgn
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4zy4B (B:)
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqmnlqqpkk
eliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaav
creclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpy
wmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpek
lsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeat