PDB entry 4zuk

View 4zuk on RCSB PDB site
Description: Structure ALDH7A1 complexed with NAD+
Class: oxidoreductase
Keywords: aldehyde dehydrogenase, nad, oxidoreductase, lysine catabolism
Deposited on 2015-05-16, released 2015-08-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-09-16, with a file datestamp of 2015-09-11.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zuka_
  • Chain 'B':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zukb_
  • Chain 'C':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zukc_
  • Chain 'D':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zukd_
  • Chain 'E':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zuke_
  • Chain 'F':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zukf_
  • Chain 'G':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zukg_
  • Chain 'H':
    Compound: Alpha-aminoadipic semialdehyde dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH7A1, ATQ1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4zukh_
  • Heterogens: PG4, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4zukA (A:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukA (A:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4zukB (B:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukB (B:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4zukC (C:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukC (C:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4zukD (D:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukD (D:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4zukE (E:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukE (E:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4zukF (F:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukF (F:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4zukG (G:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukG (G:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskd

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4zukH (H:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4zukH (H:)
tllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasvadyee
tvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvgevqey
vdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnnaiami
cgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakdervnll
sftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgtagqrc
ttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgaveeakk
eggtvvyggkvmdrpgnyveptivtglghdasiahtetfapilyvfkfkneeevfawnne
vkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggresgs
dawkqymrrstctinyskdlplaqgikfq