PDB entry 4ztj

View 4ztj on RCSB PDB site
Description: Crystal Structure of the Prototype Foamy Virus Intasome with a 2-Pyridinone Aminal Inhibitor
Class: transferase/DNA/inhibitor
Keywords: TRANSFERASE-DNA COMPLEX, DNA INTEGRATION, VIRAL PROTEIN, RECOMBINATION-INHIBITOR-DNA COMPLEX, transferase-DNA-inhibitor complex
Deposited on 2015-05-14, released 2015-10-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-11-04, with a file datestamp of 2015-10-30.
Experiment type: XRAY
Resolution: 2.67 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: PFV integrase
    Species: Human spumaretrovirus [TaxId:11963]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14350
      • conflict (219-220)
    Domains in SCOPe 2.08: d4ztja1, d4ztja2, d4ztja3
  • Chain 'B':
    Compound: PFV integrase
    Species: Human spumaretrovirus [TaxId:11963]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14350
      • conflict (219-220)
    Domains in SCOPe 2.08: d4ztjb_
  • Chain 'C':
    Compound: DNA (5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*cp*gp*cp*a)-3')
    Species: HUMAN SPUMARETROVIRUS [TaxId:11963]
  • Chain 'D':
    Compound: DNA (5'-d(*tp*gp*cp*gp*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3')
    Species: HUMAN SPUMARETROVIRUS [TaxId:11963]
  • Heterogens: ZN, GOL, MG, SO4, 4RT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ztjA (A:)
gpgcntkkpnldaeldqllqghyikgypkqytyfledgkvkvsrpegvkiippqsdrqki
vlqahnlahtgreatllkianlywwpnmrkdvvkqlgrcqqclitnasnkasgpilrpdr
pqkpfdkffidyigplppsqgylyvlvvvdgmtgftwlyptkapstsatvkslnvltsia
ipkvihsdqgaaftsstfaewakergihlefstpyhpqssgkverknsdikrlltkllvg
rptkwydllpvvqlalnntyspvlkytphqllfgidsntpfanqdtldltreeelsllqe
irtslyhpstppassrswspvvgqlvqervarpaslrprwhkpstvlkvlnprtvvildh
lgnnrtvsidnlkptshqngttndtatmdhlekne

    Sequence, based on observed residues (ATOM records): (download) 
    >4ztjA (A:)
ldaeldqllqghyikgypkqytyfledgkvkvsrpegvkiippqsdrqkivlqahnlaht
greatllkianlywwpnmrkdvvkqlgrcqqclitnasnkasgpilrpdrpqkpfdkffi
dyigplppsqgylyvlvvvdgmtgftwlyptkapstsatvkslnvltsiaipkvihsdqg
aaftsstfaewakergihlefstpyhpqssgkverknsdikrlltkllvgrptkwydllp
vvqlalnntyspvlkytphqllfgidsntpfanqdtldltreeelsllqeirtslyhpst
ppassrswspvvgqlvqervarpaslrprwhkpstvlkvlnprtvvildhlgnnrtvsid
nlkptshq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ztjB (B:)
gpgcntkkpnldaeldqllqghyikgypkqytyfledgkvkvsrpegvkiippqsdrqki
vlqahnlahtgreatllkianlywwpnmrkdvvkqlgrcqqclitnasnkasgpilrpdr
pqkpfdkffidyigplppsqgylyvlvvvdgmtgftwlyptkapstsatvkslnvltsia
ipkvihsdqgaaftsstfaewakergihlefstpyhpqssgkverknsdikrlltkllvg
rptkwydllpvvqlalnntyspvlkytphqllfgidsntpfanqdtldltreeelsllqe
irtslyhpstppassrswspvvgqlvqervarpaslrprwhkpstvlkvlnprtvvildh
lgnnrtvsidnlkptshqngttndtatmdhlekne

    Sequence, based on observed residues (ATOM records): (download) 
    >4ztjB (B:)
drpqkpfdkffidyigplppsqgylyvlvvvdgmtgftwlyptkapstsatvkslnvlts
iaipkvihsdqgaaftsstfaewakergihlefstpyhpqssgkverknsdikrlltkll
vgrptkwydllpvvqlalnntyspvlkytphqllfgidsntpfanqdtldltreeelsll
qeir

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.