PDB entry 4zru

View 4zru on RCSB PDB site
Description: X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP) in complex with 3-[2-[(2S)-pyrrolidin-2-yl]ethynyl]pyridine (TI-5180)
Class: acetylcholine binding protein
Keywords: nicotinic, acetylcholine, Ls-AChBP
Deposited on 2015-05-12, released 2015-05-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-05-27, with a file datestamp of 2015-05-22.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (0-7)
    Domains in SCOPe 2.06: d4zrua1, d4zrua2
  • Chain 'B':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (4-7)
    Domains in SCOPe 2.06: d4zrub1, d4zrub2
  • Chain 'C':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4zruc_
  • Chain 'D':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (7)
    Domains in SCOPe 2.06: d4zrud1, d4zrud2
  • Chain 'E':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4zrue_
  • Chain 'F':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (2-7)
    Domains in SCOPe 2.06: d4zruf1, d4zruf2
  • Chain 'G':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (4-7)
    Domains in SCOPe 2.06: d4zrug1, d4zrug2
  • Chain 'H':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (7)
    Domains in SCOPe 2.06: d4zruh1, d4zruh2
  • Chain 'I':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (7)
    Domains in SCOPe 2.06: d4zrui1, d4zrui2
  • Chain 'J':
    Compound: acetylcholine-binding protein
    Species: Lymnaea stagnalis [TaxId:6523]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P58154 (8-End)
      • expression tag (6-7)
    Domains in SCOPe 2.06: d4zruj1, d4zruj2
  • Heterogens: PO4, TI9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4zruA (A:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruA (A:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdptensddseyfsqysrfei
ldvtqkknsvtysccpeayedvevslnfrkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4zruB (B:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruB (B:)
dddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqqt
twsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlymps
irqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildv
tqkknsvtysccpeayedvevslnfrkkg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4zruC (C:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruC (C:)
dradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqqttwsdr
tlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirqrf
scdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqkkn
svtysccpeayedvevslnfrkk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4zruD (D:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruD (D:)
kldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqqttws
drtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirq
rfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqk
knsvtysccpeayedvevslnfrkkg

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4zruE (E:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruE (E:)
ldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqqttwsd
rtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirqr
fscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqkk
nsvtysccpeayedvevslnfrkk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4zruF (F:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruF (F:)
kddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwq
qttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlym
psirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeil
dvtqkknsvtysccpeayedvevslnfrkkg

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4zruG (G:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruG (G:)
dddkldradilynirqtsrpdviptqrrpvavsvslkfinilevneitnevdvvfwqqtt
wsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsi
rqrfscdvsgvdtesgatcrikigswthhsreisvdptseyfsqysrfeildvtqkknsv
tysccpeayedvevslnfrkk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4zruH (H:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruH (H:)
kldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqqttws
drtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirq
rfscdvsgvdtesgatcrikigswthhsreisvdptensddseyfsqysrfeildvtqkk
nsvtysccpeayedvevslnfrk

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >4zruI (I:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruI (I:)
kldradilynirqtsrpdviptdrpvavsvslkfinilevneitnevdvvfwqqttwsdr
tlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsirqrf
scdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfeildvtqkkn
svtysccpeayedvevslnfrkk

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >4zruJ (J:)
dykddddkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvf
wqqttwsdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevl
ympsirqrfscdvsgvdtesgatcrikigswthhsreisvdpttensddseyfsqysrfe
ildvtqkknsvtysccpeayedvevslnfrkkgrseil

    Sequence, based on observed residues (ATOM records): (download) 
    >4zruJ (J:)
dkldradilynirqtsrpdviptqrdrpvavsvslkfinilevneitnevdvvfwqqttw
sdrtlawnsshspdqvsvpisslwvpdlaaynaiskpevltpqlarvvsdgevlympsir
qrfscdvsgvdtesgatcrikigswthhsreisvdpnsddseyfsqysrfeildvtqkkn
svtysccpeayedvevslnfrkk