PDB entry 4zr2

View 4zr2 on RCSB PDB site
Description: Crystal Structure of the Domain-Swapped Dimer K40L:Q108K:Y60W mutant of Human Cellular Retinol Binding Protein II
Class: lipid binding protein
Keywords: Domain Swapped Dimer, Domain Swapping, Protein folding, Human Cellular Retinol Binding Protein II, Intracellular Lipid Binding Protein, Retinal, LIPID BINDING PROTEIN
Deposited on 2015-05-11, released 2016-06-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (39)
      • engineered mutation (59)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d4zr2a_
  • Chain 'B':
    Compound: Retinol-binding protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RBP2, CRBP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P50120 (0-132)
      • engineered mutation (39)
      • engineered mutation (59)
      • engineered mutation (107)
    Domains in SCOPe 2.07: d4zr2b_
  • Heterogens: RET, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4zr2A (A:)
    trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfktkttstfrnw
    dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
    cgdqvcrqvfkkk
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4zr2B (B:)
    trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfktkttstfrnw
    dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
    cgdqvcrqvfkkk