PDB entry 4z7m

View 4z7m on RCSB PDB site
Description: Novel Inhibitors of Bacterial Methionine Aminopeptidase with Broad-Spectrum Biochemical Activity
Class: hydrolase/hydrolase inhibitor
Keywords: antibacterial, methionine aminopeptidase, azepinone, structure-based design, drug discovery, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2015-04-07, released 2016-04-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-04-13, with a file datestamp of 2016-04-08.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methionine aminopeptidase
    Species: Escherichia coli [TaxId:562]
    Gene: map, Z0178, ECs0170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4z7ma_
  • Chain 'B':
    Compound: Methionine aminopeptidase
    Species: Escherichia coli [TaxId:562]
    Gene: map, Z0178, ECs0170
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4z7mb_
  • Heterogens: MN, 4L9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4z7mA (A:)
aisiktpediekmrvagrlaaevlemiepyvkpgvstgeldricndyivneqhavsaclg
yhgypksvcisinevvchgipddakllkdgdivnidvtvikdgfhgdtskmfivgkptim
gerlcritqeslylalrmvkpginlreigaaiqkfveaegfsvvreycghgigrgfheep
qvlhydsretnvvlkpgmtftiepmvnagkkeirtmkdgwtvktkdrslsaqyehtivvt
dngceiltlrkddtipaiish

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4z7mB (B:)
aisiktpediekmrvagrlaaevlemiepyvkpgvstgeldricndyivneqhavsaclg
yhgypksvcisinevvchgipddakllkdgdivnidvtvikdgfhgdtskmfivgkptim
gerlcritqeslylalrmvkpginlreigaaiqkfveaegfsvvreycghgigrgfheep
qvlhydsretnvvlkpgmtftiepmvnagkkeirtmkdgwtvktkdrslsaqyehtivvt
dngceiltlrkddtipaiish