PDB entry 4z0s

View 4z0s on RCSB PDB site
Description: F96A Mutant of Plasmodium Falciparum Triosephosphate Isomerase
Class: isomerase
Keywords: tim barrels, beta-alpha barrels, isomerase, glycolysis
Deposited on 2015-03-26, released 2016-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-04-20, with a file datestamp of 2016-04-15.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: triosephosphate isomerase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: tpi
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07412 (Start-247)
      • engineered mutation (95)
      • engineered mutation (162)
    Domains in SCOPe 2.08: d4z0sa_
  • Chain 'B':
    Compound: triosephosphate isomerase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: tpi
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07412 (Start-247)
      • engineered mutation (95)
      • engineered mutation (162)
    Domains in SCOPe 2.08: d4z0sb_
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4z0sA (A:)
markyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfs
tgiqnvskfgngsytgevsaeiakdlnieyviighaerrkyfhetdedvreklqaslknn
lkavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyeplwaigtgktatpeq
aqlvhkeirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesf
vdiiksam

    Sequence, based on observed residues (ATOM records): (download) 
    >4z0sA (A:)
arkyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfst
giqnvskfgngsytgevsaeiakdlnieyviighaerrkyfhetdedvreklqaslknnl
kavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyeplwaigtgktatpeqa
qlvhkeirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesfv
diiksam

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4z0sB (B:)
markyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfs
tgiqnvskfgngsytgevsaeiakdlnieyviighaerrkyfhetdedvreklqaslknn
lkavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyeplwaigtgktatpeq
aqlvhkeirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesf
vdiiksam

    Sequence, based on observed residues (ATOM records): (download) 
    >4z0sB (B:)
arkyfvaanwkcngtlesiksltnsfnnldfdpskldvvvfpvsvhydhtrkllqskfst
giqnvskfgngsytgevsaeiakdlnieyviighaerrkyfhetdedvreklqaslknnl
kavvcfgesleqreqnktievitkqvkafvdlidnfdnvilvyeplwatatpeqaqlvhk
eirkivkdtcgekqanqirilyggsvntencssliqqedidgflvgnaslkesfvdiiks
am