PDB entry 4yzn

View 4yzn on RCSB PDB site
Description: Humanized Roco4 bound to Compound 19
Class: transferase
Keywords: Roco-Protein, Kinase, LRRK2, Inhibitor, Roco4, transferase
Deposited on 2015-03-25, released 2015-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-10-19, with a file datestamp of 2016-10-14.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable serine/threonine-protein kinase roco4
    Species: DICTYOSTELIUM DISCOIDEUM [TaxId:44689]
    Gene: roco4, DDB_G0288251
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6XHB2 (13-286)
      • engineered mutation (101)
      • engineered mutation (155)
    Domains in SCOPe 2.08: d4yzna_
  • Heterogens: 4K5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yznA (A:)
gamggsefpksrlptladneieyekqigkggfglvhkgrlvkdksvvaikslilgdsege
temiekfqefqrevfimsnlnhpnivklyglmhnpprmvmelvpcgdlyhrlldkahpik
wsvklrlmldialgieymqnqnppivhrdlrspnillqsldenapvcakvadfglsqqsv
hsvsgllgnfqwmapetigaeeesytekadtysfamilytiltgegpfdeysygkikfin
mireeglrptipedcpprlrnvielcwsgdpkkrphfsyivkelsel

    Sequence, based on observed residues (ATOM records): (download) 
    >4yznA (A:)
ptladneieyekqigkggfglvhkgrlvkdksvvaiksliletemiekfqefqrevfims
nlnhpnivklyglmhnpprmvmelvpcgdlyhrlldkahpikwsvklrlmldialgieym
qnqnppivhrdlrspnillqsldenapvcakvadfglsqqsvhsvsgllgnfqwmapeti
gaeeesytekadtysfamilytiltgegpfdeysygkikfinmireeglrptipedcppr
lrnvielcwsgdpkkrphfsyivkelsel