PDB entry 4yxw

View 4yxw on RCSB PDB site
Description: Bovine heart mitochondrial F1-ATPase inhibited by AMP-PNP and ADP in the presence of thiophosphate.
Class: hydrolase
Keywords: hydrolase, complex, mitochondrial
Deposited on 2015-03-23, released 2015-05-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-08-05, with a file datestamp of 2015-07-31.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • variant (480)
    Domains in SCOPe 2.07: d4yxwa1, d4yxwa2, d4yxwa3
  • Chain 'B':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • variant (480)
    Domains in SCOPe 2.07: d4yxwb1, d4yxwb2, d4yxwb3
  • Chain 'C':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • variant (480)
    Domains in SCOPe 2.07: d4yxwc1, d4yxwc2, d4yxwc3
  • Chain 'D':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4yxwd1, d4yxwd2, d4yxwd3
  • Chain 'E':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4yxwe1, d4yxwe2, d4yxwe3
  • Chain 'F':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4yxwf1, d4yxwf2, d4yxwf3
  • Chain 'G':
    Compound: ATP synthase subunit gamma, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: ATP synthase subunit delta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4yxwh1, d4yxwh2
  • Chain 'I':
    Compound: ATP synthase subunit epsilon, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4yxwi_
  • Heterogens: ANP, MG, CL, TS6, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4yxwA (A:)
    ektgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
    gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
    igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
    dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
    plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
    lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
    irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
    gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
    gkirtdgkiseesdaklkeivtnflagfea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwA (A:)
    svdleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndkl
    ikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiipris
    vrepmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyc
    iyvaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdng
    khaliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggsl
    talpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtr
    amkqvagtmklelaqyrevaafaqfgsdldaatqqllsrgvrltellkqgqyspmaieeq
    vaviyagvrgyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeiv
    tnflagfea
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4yxwB (B:)
    ektgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
    gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
    igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
    dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
    plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
    lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
    irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
    gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
    gkirtdgkiseesdaklkeivtnflagfea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwB (B:)
    vdleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndkli
    kegdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiiprisv
    repmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyci
    yvaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdngk
    haliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggslt
    alpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtra
    mkqvagtmklelaqyrevaldaatqqllsrgvrltellkqgqyspmaieeqvaviyagvr
    gyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeivtnflagfea
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4yxwC (C:)
    ektgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
    gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
    igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
    dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
    plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
    lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
    irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
    gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
    gkirtdgkiseesdaklkeivtnflagfea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwC (C:)
    vdleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndkli
    kegdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiiprisv
    repmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyci
    yvaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdngk
    haliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggslt
    alpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtra
    mkqvagtmklelaqyrevaafaqfgsdldaatqqllsrgvrltellkqgqyspmaieeqv
    aviyagvrgyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeivt
    nflagfea
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4yxwD (D:)
    aaqaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlges
    tvrtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaai
    haeapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvaka
    hggysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltg
    ltvaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeri
    tttkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsr
    imdpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsq
    pfqvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaee
    hs
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwD (D:)
    ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
    lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
    eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
    rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
    qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
    aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
    dvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpfqvaevftghl
    gklvplketikgfqqilageydhlpeqafymvgpieeavakadklae
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4yxwE (E:)
    aaqaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlges
    tvrtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaai
    haeapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvaka
    hggysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltg
    ltvaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeri
    tttkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsr
    imdpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsq
    pfqvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaee
    hs
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwE (E:)
    ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
    lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
    eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
    rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
    qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
    aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
    dvargvqkilqdykslqdilseedkltvsrarkiqrflsqpfqvaevftghlgklvplke
    tikgfqqilageydhlpeqafymvgpieeavakadkla
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4yxwF (F:)
    aaqaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlges
    tvrtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaai
    haeapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvaka
    hggysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltg
    ltvaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeri
    tttkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsr
    imdpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsq
    pfqvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaee
    hs
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwF (F:)
    ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
    lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
    eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
    rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
    qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
    aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
    dvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpfqvaevftghl
    gklvplketikgfqqilageydhlpeqafymvgpieeavakadkla
    

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >4yxwH (H:)
    aeaaaaqapaagpgqmsftfasptqvffnsanvrqvdvptqtgafgilaahvptlqvlrp
    glvvvhaedgttskyfvssgsvtvnadssvqllaeeavtldmldlgaakanlekaqsell
    gaadeatraeiqirieanealvkale
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwH (H:)
    qmsftfasptqvffnsanvrqvdvptqtgafgilaahvpvlrpglvvvhaedgttskyfv
    ssgsvtvnadssvqllaeeavtldmldlgaakanlekaqsellgaadeatraeiqiriea
    nealvkal
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >4yxwI (I:)
    vaywrqaglsyirysqicakavrdalktefkanamktsgstikivkvkke
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yxwI (I:)
    vaywrqaglsyirysqicakavrdalktefkanamktsgstikivkv