PDB entry 4yw5

View 4yw5 on RCSB PDB site
Description: Crystal Structure of Streptococcus pneumoniae NanC, complex with oseltamivir carboxylate
Class: hydrolase
Keywords: Sialidase, Neuraminidase, oseltamivir, CBM40, hydrolase
Deposited on 2015-03-20, released 2015-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase C
    Species: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) [TaxId:170187]
    Gene: SP_1326,nanC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4yw5a1, d4yw5a2, d4yw5a3
  • Chain 'B':
    Compound: Neuraminidase C
    Species: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) [TaxId:170187]
    Gene: SP_1326,nanC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4yw5b1, d4yw5b2, d4yw5b3
  • Heterogens: G39, GOL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4yw5A (A:)
etpvleknnvtltgggenvtkelkdkftsgdftvvikynqssekglqalfgisnskpgqq
nsyvdvflrdngelgmeardtssnknnlvsrpasvwgkykqeavtntvavvadsvkktys
lyangtkvvekkvdnflnikdikgidyymlggvkragktafgfngtlenikffnsaldee
tvkkmttnavtghliytandttgsnyfripvlytfsngrvfssidaryggthdflnkini
atsysddngktwtkpkltlafddfapvplewprevggrdlqisggatyidsvivekknkq
vlmfadvmpagvsfreatrkdsgykqidgnyylklrkqgdtdynytirengtvyddrtnr
ptefsvdknfgikqngnyltveqysvsfennkkteyrngtkvhmnifykdalfkvvptny
iayissndhgeswsaptllppimglnrnapylgpgrgiiesstgrilipsytgkesafiy
sddngaswkvkvvplpsswsaeaqfvelspgviqaymrtnngkiayltskdagttwsape
ylkfvsnpsygtqlsiinysqlidgkkavilstpnstngrkhgqiwiglinddntidwry
hhdvdysnygysystltelpnheiglmfekfdswsrnelhmknvvpyitfkiedlkknl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4yw5B (B:)
etpvleknnvtltgggenvtkelkdkftsgdftvvikynqssekglqalfgisnskpgqq
nsyvdvflrdngelgmeardtssnknnlvsrpasvwgkykqeavtntvavvadsvkktys
lyangtkvvekkvdnflnikdikgidyymlggvkragktafgfngtlenikffnsaldee
tvkkmttnavtghliytandttgsnyfripvlytfsngrvfssidaryggthdflnkini
atsysddngktwtkpkltlafddfapvplewprevggrdlqisggatyidsvivekknkq
vlmfadvmpagvsfreatrkdsgykqidgnyylklrkqgdtdynytirengtvyddrtnr
ptefsvdknfgikqngnyltveqysvsfennkkteyrngtkvhmnifykdalfkvvptny
iayissndhgeswsaptllppimglnrnapylgpgrgiiesstgrilipsytgkesafiy
sddngaswkvkvvplpsswsaeaqfvelspgviqaymrtnngkiayltskdagttwsape
ylkfvsnpsygtqlsiinysqlidgkkavilstpnstngrkhgqiwiglinddntidwry
hhdvdysnygysystltelpnheiglmfekfdswsrnelhmknvvpyitfkiedlkknl