PDB entry 4yqs

View 4yqs on RCSB PDB site
Description: Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
Class: transferase/transferase inhibitor
Keywords: TrmD, SAM-binding, knot, transferase-transferase inhibitor complex
Deposited on 2015-03-13, released 2016-03-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-03-16, with a file datestamp of 2016-03-11.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA (guanine-N(1)-)-methyltransferase
    Species: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [TaxId:71421]
    Gene: trmD, HI_0202
    Database cross-references and differences (RAF-indexed):
    • Uniprot P43912 (8-253)
      • expression tag (6-7)
    Domains in SCOPe 2.07: d4yqsa1, d4yqsa2
  • Heterogens: 4H9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yqsA (A:)
glvprgshmwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddr
pygggpgmlmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvc
gryegiderliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfa
dglldcphytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltde
qrkllkeaqaehns

    Sequence, based on observed residues (ATOM records): (download) 
    >4yqsA (A:)
shmwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggp
gmlmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegi
derliqteideewsigdyvltggelpamtlidavarfipgvlgdglldcphytrpevleg
ltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkeaqaehns