PDB entry 4yqd

View 4yqd on RCSB PDB site
Description: Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
Class: transferase/transferase inhibitor
Keywords: TrmD, SAM-binding, knot, transferase-transferase inhibitor complex
Deposited on 2015-03-13, released 2015-11-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-11-11, with a file datestamp of 2015-11-06.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA (guanine-N(1)-)-methyltransferase
    Species: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [TaxId:71421]
    Gene: trmD, HI_0202
    Database cross-references and differences (RAF-indexed):
    • Uniprot P43912 (20-265)
      • expression tag (17-19)
    Domains in SCOPe 2.07: d4yqda1, d4yqda2
  • Heterogens: 4GZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4yqdA (A:)
    mgsshhhhhhssglvprgshmwigvislfpemfkaitefgvtgravkhnllkvecwnprd
    ftfdkhktvddrpygggpgmlmmvqplrdaihtakaaagegakviylspqgrkldqggvt
    elaqnqklilvcgryegiderliqteideewsigdyvltggelpamtlidavarfipgvl
    gkqasaeedsfadglldcphytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrr
    pelleglaltdeqrkllkeaqaehns
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yqdA (A:)
    gshmwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpyggg
    pgmlmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryeg
    iderliqteideewsigdyvltggelpamtlidavarfipgvlgasasfadglldcphyt
    rpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkeaqa
    ehns