PDB entry 4ypo

View 4ypo on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase in complex with Mg2+
Class: oxidoreductase
Keywords: ilvC, Branch chain amino acids, Knotted protein, Rossmann fold, OXIDOREDUCTASE
Deposited on 2015-03-13, released 2016-02-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-04-27, with a file datestamp of 2016-04-22.
Experiment type: XRAY
Resolution: 1 Å
R-factor: N/A
AEROSPACI score: 0.82 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ketol-acid reductoisomerase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: ilvC, IQ45_13380, IU12_14180, IU13_13535, IU21_13700, T209_13330
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ypoa1, d4ypoa2
  • Chain 'B':
    Compound: Ketol-acid reductoisomerase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: ilvC, IQ45_13380, IU12_14180, IU13_13535, IU21_13700, T209_13330
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ypob1, d4ypob2
  • Heterogens: MG, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ypoA (A:)
mfydddadlsiiqgrkvgvigygsqghahslslrdsgvqvrvglkqgsrsrpkveeqgld
vdtpaevakwadvvmvlapdtaqaeifagdiepnlkpgdalffghglnvhfglikppadv
avamvapkgpghlvrrqfvdgkgvpclvaveqdprgdglalalsyakaiggtragviktt
fkdetetdlfgeqtvlcggteelvkagfevmveagypaelayfevlhelklivdlmyegg
larmyysvsdtaefggylsgprvidagtkermrdilreiqdgsfvhklvadveggnkqle
elrrqnaehpievvgkklrdlmswvdrpiteta

    Sequence, based on observed residues (ATOM records): (download) 
    >4ypoA (A:)
mfydddadlsiiqgrkvgvigygsqghahslslrdsgvqvrvglkqgsrsrpkveeqgld
vdtpaevakwadvvmvlapdtaqaeifagdiepnlkpgdalffghglnvhfglikppadv
avamvapkgpghlvrrqfvdgkgvpclvaveqdprgdglalalsyakaiggtragviktt
fkdetetdlfgeqtvlcggteelvkagfevmveagypaelayfevlhelklivdlmyegg
larmyysvsdtaefggylsgprvidagtkermrdilreiqdgsfvhklvadveggnkqle
elrrqnaehpievvgkklrdlmswv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ypoB (B:)
mfydddadlsiiqgrkvgvigygsqghahslslrdsgvqvrvglkqgsrsrpkveeqgld
vdtpaevakwadvvmvlapdtaqaeifagdiepnlkpgdalffghglnvhfglikppadv
avamvapkgpghlvrrqfvdgkgvpclvaveqdprgdglalalsyakaiggtragviktt
fkdetetdlfgeqtvlcggteelvkagfevmveagypaelayfevlhelklivdlmyegg
larmyysvsdtaefggylsgprvidagtkermrdilreiqdgsfvhklvadveggnkqle
elrrqnaehpievvgkklrdlmswvdrpiteta

    Sequence, based on observed residues (ATOM records): (download) 
    >4ypoB (B:)
mfydddadlsiiqgrkvgvigygsqghahslslrdsgvqvrvglkqgsrsrpkveeqgld
vdtpaevakwadvvmvlapdtaqaeifagdiepnlkpgdalffghglnvhfglikppadv
avamvapkgpghlvrrqfvdgkgvpclvaveqdprgdglalalsyakaiggtragviktt
fkdetetdlfgeqtvlcggteelvkagfevmveagypaelayfevlhelklivdlmyegg
larmyysvsdtaefggylsgprvidagtkermrdilreiqdgsfvhklvadveggnkqle
elrrqnaehpievvgkklrdlmswv