PDB entry 4yhl

View 4yhl on RCSB PDB site
Description: Reversal Agent for Dabigatran
Class: immune system
Keywords: Antibody, Dabigatran, Pradaxa, Antidote, Reversal Agent, immune system
Deposited on 2015-02-27, released 2016-01-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2016-01-13, with a file datestamp of 2016-01-08.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: aDabi-Fab2b heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4YHL (0-End)
  • Chain 'L':
    Compound: aDabi-Fab2b light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4YHL (0-End)
    Domains in SCOPe 2.05: d4yhll1, d4yhll2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4yhlL (L:)
divmtqtplslsvtpgqpasiscrssqsivhsdgniylewylqkpgqspklliykvsyrf
sgvpdrfsgsgsgtgftlkisrveaedvgvyycfqashvpytfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >4yhlL (L:)
divmtqtplslsvtpgqpasiscrssqsivhsdgniylewylqkpgqspklliykvsyrf
sgvpdrfsgsgsgtgftlkisrveaedvgvyycfqashvpytfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrge