PDB entry 4ycc

View 4ycc on RCSB PDB site
Description: Structure of a single tryptophan mutant of Acetobacter aceti PurE with Y154L mutation
Class: isomerase
Keywords: acidophile, PurE, purine biosynthesis, ISOMERASE
Deposited on 2015-02-19, released 2016-02-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-06-01, with a file datestamp of 2016-05-27.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N5-carboxyaminoimidazole ribonucleotide mutase
    Species: Acetobacter aceti 1023 [TaxId:1457393]
    Gene: purE, AZ09_02690
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A063X4U8
      • engineered mutation (34)
      • engineered mutation (154)
      • engineered mutation (165)
    Domains in SCOPe 2.07: d4ycca_
  • Chain 'B':
    Compound: N5-carboxyaminoimidazole ribonucleotide mutase
    Species: Acetobacter aceti 1023 [TaxId:1457393]
    Gene: purE, AZ09_02690
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A063X4U8
      • engineered mutation (34)
      • engineered mutation (154)
      • engineered mutation (165)
    Domains in SCOPe 2.07: d4yccb_
  • Heterogens: EDO, SO4, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4yccA (A:)
    mmsetaplpsassaledkaasapvvgiimgsqsdfetmrhadallteleiphetlivsah
    rtpdrladyartaaerglnviiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsll
    sivqmpggvpvgtlaigasgaknaallaasilallnpalaarletfralqtasvpnspit
    edk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yccA (A:)
    sapvvgiimgsqsdfetmrhadallteleiphetlivsahrtpdrladyartaaerglnv
    iiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsllsivqmpggvpvgtlaigasg
    aknaallaasilallnpalaarletfralqtasvpnspit
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4yccB (B:)
    mmsetaplpsassaledkaasapvvgiimgsqsdfetmrhadallteleiphetlivsah
    rtpdrladyartaaerglnviiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsll
    sivqmpggvpvgtlaigasgaknaallaasilallnpalaarletfralqtasvpnspit
    edk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4yccB (B:)
    sapvvgiimgsqsdfetmrhadallteleiphetlivsahrtpdrladyartaaerglnv
    iiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsllsivqmpggvpvgtlaigasg
    aknaallaasilallnpalaarletfralqtasvpnspit