PDB entry 4y9c
View 4y9c on RCSB PDB site
Description: Crystal structure of V30M mutated transthyretin with bromide in complex with alpha-mangostin
Class: transport protein/inhibitor
Keywords: transthyretin, natural product, inhibitor, transporter, TRANSPORT PROTEIN-INHIBITOR complex
Deposited on
2015-02-17, released
2015-09-09
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-09-09, with a file datestamp of
2015-09-04.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4y9ca_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4y9cb_ - Heterogens: MKS, BR, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4y9cA (A:)
mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
amhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
ehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>4y9cA (A:)
cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4y9cB (B:)
mrgshhhhhhgsmashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainv
amhvfrkaaddtwepfasgktsesgelhgltteeefvegiykveidtksywkalgispfh
ehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>4y9cB (B:)
cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsrytiaallspysysttavvtn