PDB entry 4xya

View 4xya on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-amine-9H-purine ligand
Class: transcription
Keywords: Bromodomain, ligand, complex, Structural Genomics Consortium, SGC, Transcription
Deposited on 2015-02-02, released 2015-03-11
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-03-11, with a file datestamp of 2015-03-06.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (0-126)
    • conflict (1)
  Domains in SCOPe 2.05: d4xyaa_
• Heterogens: 43S, EDO, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4xyaA (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee