PDB entry 4xx7

View 4xx7 on RCSB PDB site
Description: Crystal structure of M2A mutant of human macrophage migration inhibitory factor
Class: isomerase
Keywords: Isomerase, surface, mutation
Deposited on 2015-01-29, released 2015-09-30
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-09-30, with a file datestamp of 2015-09-25.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (1)
  Domains in SCOPe 2.05: d4xx7a_
• Chain 'B':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (1)
  Domains in SCOPe 2.05: d4xx7b_
• Chain 'C':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (1)
  Domains in SCOPe 2.05: d4xx7c_
• Heterogens: SO4, IPA, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4xx7A (A:)
  pafivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4xx7B (B:)
  pafivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4xx7C (C:)
  pafivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa