PDB entry 4xsd

View 4xsd on RCSB PDB site
Description: Complex structure of thymidylate synthase from varicella zoster virus with a dUMP
Class: viral protein
Keywords: VZV, thymidylate synthase, herpesvirus, viral protein
Deposited on 2015-01-22, released 2015-12-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-12-16, with a file datestamp of 2015-12-11.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4xsda_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4xsdb_
  • Chain 'C':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4xsdc_
  • Chain 'D':
    Compound: Thymidylate synthase
    Species: Varicella-zoster virus (strain Oka vaccine) [TaxId:341980]
    Gene: ORF13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4xsdd_
  • Heterogens: UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xsdA (A:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xsdA (A:)
ltgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravve
ellwfirgstdskelaakdihiwgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvi
dtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpf
niagyalltyivahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnv
tdindfkwddfqldgynphppl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4xsdB (B:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xsdB (B:)
tltgelqylkqvddilrygvrkrdgigtlslfgmqarynlrnefpllttkrvfwravvee
llwfirgstdskelaakdihiwdiygsskflnrngfhkrhtgdlgpiygfqwrhfgaeyk
snylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangelsc
qvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkvqla
rspkpfpclkiirnvtdindfkwddfqldgynphppl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4xsdC (C:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xsdC (C:)
tgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravvee
llwfirgstdskelaakdihiwdidlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvi
dtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpf
niagyalltyivahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnv
tdindfkwddfqldgynphppl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4xsdD (D:)
mhhhhhhssgvdlgtenlyfqsmtkvpgftltgelqylkqvddilrygvrkrdrtgigtl
slfgmqarynlrnefpllttkrvfwravveellwfirgstdskelaakdihiwdiygssk
flnrngfhkrhtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvidtiktnpesrr
miisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpfniagyalltyi
vahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnvtdindfkwddf
qldgynphppl

    Sequence, based on observed residues (ATOM records): (download) 
    >4xsdD (D:)
tltgelqylkqvddilrygvrkrdgigtlslfgmqarynlrnefpllttkrvfwravvee
llwfirgstdskelaakdihiwdiygsskflnrngfhkrhtgdlgpiygfqwrhfgaeyk
dcqsnylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvange
lscqvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkv
qlarspkpfpclkiirnvtdindfkwddfqldgynphppl