PDB entry 4xrc

View 4xrc on RCSB PDB site
Description: Antibody hemagglutinin Complexes
Class: viral protein/immune system
Keywords: Antibody, hemagglutinin, neutralization, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2015-01-20, released 2015-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.74 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: H5.3 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4XRC (0-207)
    Domains in SCOPe 2.08: d4xrca1, d4xrca2
  • Chain 'B':
    Compound: H5.3 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4XRC (0-End)
    Domains in SCOPe 2.08: d4xrcb1, d4xrcb2
  • Chain 'C':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6Q9G9 (0-End)
      • engineered mutation (108)
      • engineered mutation (174)
      • engineered mutation (176)
  • Chain 'D':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6Q9G9 (0-End)
      • engineered mutation (108)
      • engineered mutation (174)
      • engineered mutation (176)
  • Chain 'H':
    Compound: H5.3 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4XRC (0-End)
    Domains in SCOPe 2.08: d4xrch1, d4xrch2
  • Chain 'L':
    Compound: H5.3 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4XRC (0-207)
    Domains in SCOPe 2.08: d4xrcl1, d4xrcl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4xrcA (A:)
yeltqppsvsvspgqtvnitcsgdtlgdkyvcwyqqkpgqspvlviyqdtkrpsgiperf
sgsnsgdtatltvsgtqamdeadyycqawdsssfvfgtgtkvtvlgqpkanptvtlfpps
seelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaassylslt
peqwkshrsyscqvthegstvektvapt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4xrcB (B:)
qvqlqesgpglvkpsgtvsltcavsggsisssywwswvrqppgkglewigeiyhsgntny
npslksrvtisvdksknlfslklssvtaadtavyycarvalfdiltggwfdpwgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvelktpt

    Sequence, based on observed residues (ATOM records): (download) 
    >4xrcB (B:)
qvqlqesgpglvkpsgtvsltcavsggsisssywwswvrqppgkglewigeiyhsgntny
npslksrvtisvdksknlfslklssvtaadtavyycarvalfdiltggwfdpwgqgtlvt
vssastkgpsvfplapsaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysl
ssvvtvpssslgtqtyicnvnhkpsntkvdkrvel

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4xrcH (H:)
qvqlqesgpglvkpsgtvsltcavsggsisssywwswvrqppgkglewigeiyhsgntny
npslksrvtisvdksknlfslklssvtaadtavyycarvalfdiltggwfdpwgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvelktpt

    Sequence, based on observed residues (ATOM records): (download) 
    >4xrcH (H:)
qvqlqesgpglvkpsgtvsltcavsggsisssywwswvrqppgkglewigeiyhsgntny
npslksrvtisvdksknlfslklssvtaadtavyycarvalfdiltggwfdpwgqgtlvt
vssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvel

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4xrcL (L:)
yeltqppsvsvspgqtvnitcsgdtlgdkyvcwyqqkpgqspvlviyqdtkrpsgiperf
sgsnsgdtatltvsgtqamdeadyycqawdsssfvfgtgtkvtvlgqpkanptvtlfpps
seelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaassylslt
peqwkshrsyscqvthegstvektvapt