PDB entry 4xjs

View 4xjs on RCSB PDB site
Description: Human CD38 complexed with inhibitor 1 [6-fluoro-2-methyl-4-[(2,3,6-trichlorobenzyl)amino]quinoline-8-carboxamide]
Class: Hydrolase, Transferase
Keywords: CD38, Hydrolase, Transferase
Deposited on 2015-01-09, released 2015-08-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-09-23, with a file datestamp of 2015-09-18.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD38
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28907 (7-End)
      • engineered mutation (61)
      • engineered mutation (125)
      • engineered mutation (170)
      • engineered mutation (180)
    Domains in SCOPe 2.07: d4xjsa_
  • Heterogens: 733, HSX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xjsA (A:)
rgknpedwrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhp
cditeedyqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdlt
wcgefatskinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdk
dstfgsvevhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckni
yrpdkflqcvknpedssctsei

    Sequence, based on observed residues (ATOM records): (download) 
    >4xjsA (A:)
wrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefat
skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
evhnlqpekvqtleawvihgsrdlcqdptikelesiiskrniqfsckniyrpdkflqcv