PDB entry 4xjj

View 4xjj on RCSB PDB site
Description: Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201
Class: Cytokine Receptor
Keywords: type II Transforming Growth Factor Beta receptor, NDSB-201, Transforming Growth Factor Beta, kinase, extracellular domain
Deposited on 2015-01-08, released 2015-06-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-06-24, with a file datestamp of 2015-06-19.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TGF-beta receptor type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37173 (2-End)
      • expression tag (1)
      • engineered mutation (72)
    Domains in SCOPe 2.06: d4xjja1, d4xjja2
  • Heterogens: 41D, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4xjjA (A:)
    malckfcdvrfstcdnqkscmsncsitsicekpqevcvavwrkndenitletvchdpklp
    yhdfiledaasptcimkekkkpgetffmcscssdecndniifseeyntsnpd
    

    Sequence, based on observed residues (ATOM records): (download)
    >4xjjA (A:)
    alckfcdvrfstcdnqkscmsncsitsicekpqevcvavwrkndenitletvchdpklpy
    hdfiledaasptcimkekkkpgetffmcscssdecndniifseey