PDB entry 4xde

View 4xde on RCSB PDB site
Description: Coagulation Factor XII protease domain crystal structure
Class: blood clotting
Keywords: Factor XII, catalytic domain, Zymogens, hydrolase, blood clotting
Deposited on 2014-12-19, released 2015-02-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-10-28, with a file datestamp of 2015-10-23.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Coagulation factor XII
    Species: Homo sapiens [TaxId:9606]
    Gene: F12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00748 (Start-244)
      • engineered mutation (115)
      • expression tag (245-247)
    Domains in SCOPe 2.08: d4xdea1, d4xdea2
  • Heterogens: IPA, FLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xdeA (A:)
rsvvgglvalrgahpyiaalywghsfcagsliapcwvltaahclqdrpapedltvvlgqe
rrnhscepcqtlavrsyrlheafspvsyqhdlallrlqedadgscallspyvqpvslpsg
aarpsettlcqvagwghqfegaeeyasflqeaqvpflslercsapdvhgssilpgmlcag
fleggtdacqgdsggplvcedqaaerrltlqgiiswgsgcgdrnkpgvytdvayylawir
ehtvshhtgtrhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4xdeA (A:)
valrgahpyiaalywghsfcagsliapcwvltaahclqdrpapedltvvlgqerrnhsce
pcqtlavrsyrlheafspvsyqhdlallrlqedadgscallspyvqpvslpsgaarpset
tlcqvagwghqfegaeeyasflqeaqvpflslercsapdvhgssilpgmlcagfleggtd
acqgdsggplvcedqaaerrltlqgiiswgsgcgdrnkpgvytdvayylawirehtvshh
t