PDB entry 4xay

View 4xay on RCSB PDB site
Description: Cycles of destabilization and repair underlie evolutionary transitions in enzymes
Class: hydrolase
Keywords: dynamics, evolution, phosphotriesterase, HYDROLASE
Deposited on 2014-12-16, released 2015-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-10-26, with a file datestamp of 2016-10-21.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphotriesterase variant PTE-R8
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4xaya_
  • Chain 'G':
    Compound: Phosphotriesterase variant PTE-R8
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4xayg_
  • Heterogens: ZN, MPD, CAC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4xayA (A:)
mgdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrara
agvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsirlrsveeltqfflr
eiqygiedtgiragiikvaitgkvtpfqelvlraaaraslatgvpvithtaasqrggeqq
aaifeseglspsrvcighsdetddlsyltalaargyligldriphsaiglednasatall
gsrswqtrallikalidqgymkqilvsndwlfgissyvtnimdvmdsvnpdgmafiplrv
ipflrekgipqetlagitvtnparflsptlras

    Sequence, based on observed residues (ATOM records): (download) 
    >4xayA (A:)
gdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrraraa
gvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsirlrsveeltqfflre
iqygiedtgiragiikvaitgkvtpfqelvlraaaraslatgvpvithtaasqrggeqqa
aifeseglspsrvcighsdetddlsyltalaargyligldriphsaiglednasatallg
srswqtrallikalidqgymkqilvsndwlfgissyvtnimdvmdsvnpdgmafiplrvi
pflrekgipqetlagitvtnparflsptlr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4xayG (G:)
mgdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrara
agvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsirlrsveeltqfflr
eiqygiedtgiragiikvaitgkvtpfqelvlraaaraslatgvpvithtaasqrggeqq
aaifeseglspsrvcighsdetddlsyltalaargyligldriphsaiglednasatall
gsrswqtrallikalidqgymkqilvsndwlfgissyvtnimdvmdsvnpdgmafiplrv
ipflrekgipqetlagitvtnparflsptlras

    Sequence, based on observed residues (ATOM records): (download) 
    >4xayG (G:)
gdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrraraa
gvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsirlrsveeltqfflre
iqygiedtgiragiikvaitgkvtpfqelvlraaaraslatgvpvithtaasqrggeqqa
aifeseglspsrvcighsdetddlsyltalaargyligldriphsaiglednasatallg
srswqtrallikalidqgymkqilvsndwlfgissyvtnimdvmdsvnpdgmafiplrvi
pflrekgipqetlagitvtnparflsptl