PDB entry 4x6c

View 4x6c on RCSB PDB site
Description: CD1a ternary complex with lysophosphatidylcholine and BK6 TCR
Class: immune system
Keywords: CD1a, TCR, Immune complex, Lipid antigen, IMMUNE SYSTEM
Deposited on 2014-12-08, released 2015-01-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-03-04, with a file datestamp of 2015-02-27.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein CD1a
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06126 (Start-274)
      • variant (9)
      • variant (47)
    Domains in SCOPe 2.07: d4x6ca1, d4x6ca2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x6cb_
  • Chain 'C':
    Compound: T-cell surface glycoprotein CD1a
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06126
      • variant (9)
      • variant (47)
    Domains in SCOPe 2.07: d4x6cc1
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x6cd_
  • Chain 'E':
    Compound: tcr alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6C
    Domains in SCOPe 2.07: d4x6ce1, d4x6ce2
  • Chain 'F':
    Compound: tcr beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6C (0-End)
    Domains in SCOPe 2.07: d4x6cf1, d4x6cf2
  • Chain 'G':
    Compound: tcr alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6C
    Domains in SCOPe 2.07: d4x6cg1, d4x6cg2
  • Chain 'H':
    Compound: tcr beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4X6C
    Domains in SCOPe 2.07: d4x6ch1, d4x6ch2
  • Heterogens: NAG, 42H, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x6cA (A:)
lkeplsfhviwiasfynhswkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneew
keletlfrirtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdf
vsfqnnswlpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqr
qvkpeawlshgpspgpghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtw
ylratlevaageaadlscrvkhsslegqdivlywegslvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cA (A:)
plsfhviwianlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneewkeletlfrirti
rsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdfvsfqnnswlpyp
vagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqrqvkpeawlshgp
spgpghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtwylratlevaage
aadlscrvkhsslegqdivlywe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4x6cB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmgslvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4x6cC (C:)
lkeplsfhviwiasfynhswkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneew
keletlfrirtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdf
vsfqnnswlpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqr
qvkpeawlshgpspgpghlqlvchvsgfypkpvwvmwmrgeqeqqgtqrgdilpsadgtw
ylratlevaageaadlscrvkhsslegqdivlywegslvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cC (C:)
plsfhviwiasfynhswkqnlvsgwlsdlqthtwdsnsstivflwpwsrgnfsneewkel
etlfrirtirsfegirryahelqfeypfeiqvtggcelhsgkvsgsflqlayqgsdfvsf
qnnswlpypvagnmakhfckvlnqnqhendithnllsdtcprfilglldagkahlqrqvk
peawlshqlvchvsgfypkpvwvmwmrgeqrgdilpsadgtwylratledlscrvkhssl
egqdivlyw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4x6cD (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmgslvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cD (D:)
iqrtpkiqvysrhflncyvsgfhpsdievdllkngeriekvehsdlsfskdwsfyllyyt
eftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4x6cE (E:)
qkeveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgr
ftaqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdp
avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
ksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cE (E:)
keveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgrf
taqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdpa
vyqlrddksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfa
canafnnsiipedtffps

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4x6cF (F:)
nagvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgev
pdgynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnk
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cF (F:)
nagvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgev
pdgynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnk
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4x6cG (G:)
qkeveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgr
ftaqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdp
avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
ksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cG (G:)
keveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgrf
taqvdksskyislfirdsqpsdsatylcamstslpnagkstfgdgttltvkpniqnpdpa
vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnk
sdfacanafnnsiipedtffp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4x6cH (H:)
nagvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgev
pdgynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnk
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4x6cH (H:)
agvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgevp
dgynvsrlkkqnfllglesaapsqtsvyfcasryflptqgmgaffgqgtrltvvedlnkv
fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeq
palndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
gra