PDB entry 4x5i

View 4x5i on RCSB PDB site
Description: ecDHFR complexed with folate and NADP+ at 660 MPa
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2014-12-05, released 2016-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-09-19, with a file datestamp of 2018-09-14.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Escherichia coli K12 [TaxId:83333]
    Gene: folA, tmrA, b0048, JW0047
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4x5ia_
  • Heterogens: FOL, NAP, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x5iA (A:)
gshmisliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgr
kniilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthida
evegdthfpdyepddwesvfsefhdadaqnshsycfeilerr

    Sequence, based on observed residues (ATOM records): (download) 
    >4x5iA (A:)
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr