PDB entry 4x5f
View 4x5f on RCSB PDB site
Description: ecDHFR complexed with folate and NADP+ at 0.1 MPa
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on
2014-12-05, released
2016-01-13
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-09-27, with a file datestamp of
2017-09-22.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Escherichia coli K12 [TaxId:83333]
Gene: folA, tmrA, b0048, JW0047
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4x5fa_ - Chain 'B':
Compound: dihydrofolate reductase
Species: Escherichia coli K12 [TaxId:83333]
Gene: folA, tmrA, b0048, JW0047
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4x5fb1, d4x5fb2 - Heterogens: FOL, NAP, BME, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4x5fA (A:)
gshmisliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgr
kniilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthida
evegdthfpdyepddwesvfsefhdadaqnshsycfeilerr
Sequence, based on observed residues (ATOM records): (download)
>4x5fA (A:)
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4x5fB (B:)
gshmisliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgr
kniilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthida
evegdthfpdyepddwesvfsefhdadaqnshsycfeilerr
Sequence, based on observed residues (ATOM records): (download)
>4x5fB (B:)
hmisliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkn
iilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaev
egdthfpdyepddwesvfsefhdadaqnshsycfeilerr