PDB entry 4x55

View 4x55 on RCSB PDB site
Description: Structure of the class D Beta-Lactamase OXA-225 K82D in Acyl-Enzyme Complex with Ceftazidime
Class: hydrolase
Keywords: Hydrolase, Carbapenemase, Antibiotic
Deposited on 2014-12-04, released 2015-03-11
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-03-11, with a file datestamp of 2015-03-06.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase OXA-225
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: blaOXA-225, oxa23
    Database cross-references and differences (RAF-indexed):
    • Uniprot G5DE28 (Start-252)
      • engineered mutation (61)
    Domains in SCOPe 2.05: d4x55a_
  • Chain 'B':
    Compound: Beta-lactamase OXA-225
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: blaOXA-225, oxa23
    Database cross-references and differences (RAF-indexed):
    • Uniprot G5DE28 (Start-252)
      • engineered mutation (61)
    Domains in SCOPe 2.05: d4x55b_
  • Heterogens: CTJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x55A (A:)
mhnlinetpsqivqghnqvihqyfdekntsgvlviqtdkkinlygnalsranteyvpast
fdmlnaliglenqktdineifkwkgekrsftawekdmtlgeamklsavpvyqelarrigl
dlmqkevkrigfgnaeigqqvdnfwlvgplkvtpiqevefvsqlahtqlpfsekvqanvk
nmllleesngykifgktgwamdiksqvgwltgwveqpdgkivafalnmemrsempasirn
ellmkslkqlnii

    Sequence, based on observed residues (ATOM records): (download) 
    >4x55A (A:)
qivqghnqvihqyfdekntsgvlviqtdkkinlygnalsranteyvpastfdmlnaligl
enqktdineifkwkgekrsftawekdmtlgeamklsavpvyqelarrigldlmqkevkri
gfgnaeigqqvdnfwlvgplkvtpiqevefvsqlahtqlpfsekvqanvknmllleesng
ykifgktgwamdiksqvgwltgwveqpdgkivafalnmemrsempasirnellmkslkql
nii

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4x55B (B:)
mhnlinetpsqivqghnqvihqyfdekntsgvlviqtdkkinlygnalsranteyvpast
fdmlnaliglenqktdineifkwkgekrsftawekdmtlgeamklsavpvyqelarrigl
dlmqkevkrigfgnaeigqqvdnfwlvgplkvtpiqevefvsqlahtqlpfsekvqanvk
nmllleesngykifgktgwamdiksqvgwltgwveqpdgkivafalnmemrsempasirn
ellmkslkqlnii

    Sequence, based on observed residues (ATOM records): (download) 
    >4x55B (B:)
nqvihqyfdekntsgvlviqtdkkinlygnalsranteyvpastfdmlnaliglenqktd
ineifgekrsftawkdmtlgeamklsavpvyqelarrigldlmqkevkrigfgnaeigqq
vdnfwlvgplkvtpiqevefvsqlahtqlpfsekvqanvknmllleesngykifgktgwa
mdksqvgwltgwveqpdgkivafalnmemrsempasirnellmkslkqlnii