PDB entry 4x1l

View 4x1l on RCSB PDB site
Description: Structural basis for mutation-induced destabilization of Profilin 1 in ALS
Class: protein binding
Keywords: als, protein binding
Deposited on 2014-11-24, released 2015-06-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Profilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PFN1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4x1la_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4x1lA (A:)
magwnayidnlmadgtcqdaaivgykdspsvwaavpgktfvnitpaevgvlvgkdrssfy
vngltlggqkcsvirdsllqdgefsmdlrtkstggaptfnvtvtktdktlvllmgkegvh
gglinkkcyemashlrrsqy

    Sequence, based on observed residues (ATOM records): (download) 
    >4x1lA (A:)
gwnayidnlmadgtcqdaaivgykdspsvwaavpgktfvnitpaevgvlvgkdrgltlgg
qkcsvirdsllqdgefsmdlrtkptfnvtvtktdktlvllmgkegvhgglinkkcyemas
hlrrsqy