PDB entry 4wxg

View 4wxg on RCSB PDB site
Description: Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine
Class: transferase
Keywords: Aldolase, Transferase, Aldehydes, Catalysis, Catalytic Domain, Dimerization, Glycine Hydroxymethyltransferase, L-allo-Threonine, protein Binding, Threonine aldolase
Deposited on 2014-11-13, released 2015-02-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-25, with a file datestamp of 2020-03-20.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine hydroxymethyltransferase
    Species: Streptococcus thermophilus [TaxId:299768]
    Gene: glyA, str0755
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wxga_
  • Chain 'C':
    Compound: serine hydroxymethyltransferase
    Species: Streptococcus thermophilus [TaxId:299768]
    Gene: glyA, str0755
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wxgc_
  • Heterogens: 2BO, GOL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wxgA (A:)
mrgshhhhhhgsmifdkedykafdpelwnaidaeaerqqnnieliasenvvskavmaaqg
tlltnkyaegypgkryyggtavidvvetlaierakklfgakfanvqphsgsqanaavyms
liqpgdtvmgmdlsagghlthgapvsfsgktynfvsynvdkeselldydailaqakevrp
klivagasaysriidfakfreiadavgaylmvdmahiaglvasghhpspvpyahvttttt
hktlrgprggliltddediakklnsavfpglqggplehviaakavalkealdpafkeyge
nviknaaamadvfnqhpdfrvisggtnnhlflvdvtkvvengkvaqnvleevnitlnkns
ipyeqlspfktsgirvgspaitsrgmgeaesrqiaewmvealenhdkpevlerirgdvkv
ltdafply

    Sequence, based on observed residues (ATOM records): (download) 
    >4wxgA (A:)
dykafdpelwnaidaeaerqqnnieliasenvvskavmaaqgtlltnkyaegypgkryyg
gtavidvvetlaierakklfgakfanvqphsgsqanaavymsliqpgdtvmgmdlsaggh
lthgapvsfsgktynfvsynvdkeselldydailaqakevrpklivagasaysriidfak
freiadavgaylmvdmahiaglvasghhpspvpyahvttttthktlrgprggliltdded
iakklnsavfpglqggplehviaakavalkealdpafkeygenviknaaamadvfnqhpd
frvisggtnnhlflvdvtkvvengkvaqnvleevnitlnknsipyeqlspfktsgirvgs
paitsrgmgeaesrqiaewmvealenhdkpevlerirgdvkvltdafply

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4wxgC (C:)
mrgshhhhhhgsmifdkedykafdpelwnaidaeaerqqnnieliasenvvskavmaaqg
tlltnkyaegypgkryyggtavidvvetlaierakklfgakfanvqphsgsqanaavyms
liqpgdtvmgmdlsagghlthgapvsfsgktynfvsynvdkeselldydailaqakevrp
klivagasaysriidfakfreiadavgaylmvdmahiaglvasghhpspvpyahvttttt
hktlrgprggliltddediakklnsavfpglqggplehviaakavalkealdpafkeyge
nviknaaamadvfnqhpdfrvisggtnnhlflvdvtkvvengkvaqnvleevnitlnkns
ipyeqlspfktsgirvgspaitsrgmgeaesrqiaewmvealenhdkpevlerirgdvkv
ltdafply

    Sequence, based on observed residues (ATOM records): (download) 
    >4wxgC (C:)
dykafdpelwnaidaeaerqqnnieliasenvvskavmaaqgtlltnkyaegypgkryyg
gtavidvvetlaierakklfgakfanvqphsgsqanaavymsliqpgdtvmgmdlsaggh
lthgapvsfsgktynfvsynvdkeselldydailaqakevrpklivagasaysriidfak
freiadavgaylmvdmahiaglvasghhpspvpyahvttttthktlrgprggliltdded
iakklnsavfpglqggplehviaakavalkealdpafkeygenviknaaamadvfnqhpd
frvisggtnnhlflvdvtkvvengkvaqnvleevnitlnknsipyeqlspfktsgirvgs
paitsrgmgeaesrqiaewmvealenhdkpevlerirgdvkvltdafply