PDB entry 4wwy

View 4wwy on RCSB PDB site
Description: human cationic trypsin G193R mutant in complex with bovine pancreatic trypsin inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: trypsin inhibitors, complex, BPTI, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-11-12, released 2015-07-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-09-09, with a file datestamp of 2015-09-04.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Trypsin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRSS1, TRP1, TRY1, TRYP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07477 (0-223)
      • engineered mutation (98)
      • engineered mutation (174)
    Domains in SCOPe 2.06: d4wwya_
  • Chain 'B':
    Compound: Trypsin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRSS1, TRP1, TRY1, TRYP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07477 (0-223)
      • engineered mutation (98)
      • engineered mutation (174)
    Domains in SCOPe 2.06: d4wwyb_
  • Chain 'C':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4wwyc_
  • Chain 'I':
    Compound: pancreatic trypsin inhibitor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4wwyi_
  • Heterogens: SO4, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4wwyA (A:)
    ivggynceensvpyqvslnsgyhfcggslineqwvvsaghcyksriqvrlgehnievleg
    neqfinaakiirhpqydrktlnndimliklssravinahvstislptappatgtkclisg
    wgntassgadypdelqcldapvlsqakceasypgkitsnmfcvgfleggkdscqrdsggp
    vvcngqlqgvvswgdgcaqknkpgvytkvynyvkwikntiaans
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4wwyB (B:)
    ivggynceensvpyqvslnsgyhfcggslineqwvvsaghcyksriqvrlgehnievleg
    neqfinaakiirhpqydrktlnndimliklssravinahvstislptappatgtkclisg
    wgntassgadypdelqcldapvlsqakceasypgkitsnmfcvgfleggkdscqrdsggp
    vvcngqlqgvvswgdgcaqknkpgvytkvynyvkwikntiaans
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4wwyC (C:)
    rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga
    

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4wwyI (I:)
    rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga