PDB entry 4wwq

View 4wwq on RCSB PDB site
Description: Apo structure of the Grb7 SH2 domain
Class: signaling protein
Keywords: src Homology Domain, phosphotyrosine binding pocket, SIGNALING PROTEIN
Deposited on 2014-11-12, released 2015-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Growth factor receptor-bound protein 7
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wwqa_
  • Chain 'B':
    Compound: Growth factor receptor-bound protein 7
    Species: Homo sapiens [TaxId:9606]
    Gene: GRB7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14451 (2-119)
      • expression tag (1)
    Domains in SCOPe 2.08: d4wwqb1, d4wwqb2
  • Heterogens: MLA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4wwqA (A:)
    gspasgtslsaaihrtqlwfhgrisreesqrligqqglvdglflvresqrnpqgfvlslc
    hlqkvkhylilpseeegrlyfsmddgqtrftdllqlvefhqlnrgilpcllrhcctrval
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wwqA (A:)
    lsaaihrtqlwfhgrisreesqrligqqglvdglflvresqrnpqgfvlslchlqkvkhy
    lilpseeegrlyfsmddgqtrftdllqlvefhqlnrgilpcllrhcctrval
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4wwqB (B:)
    gspasgtslsaaihrtqlwfhgrisreesqrligqqglvdglflvresqrnpqgfvlslc
    hlqkvkhylilpseeegrlyfsmddgqtrftdllqlvefhqlnrgilpcllrhcctrval
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wwqB (B:)
    spasgtslsaaihrtqlwfhgrisreesqrligqqglvdglflvresqrnpqgfvlslch
    lqkvkhylilpseeegrlyfsmddgqtrftdllqlvefhqlnrgilpcllrhcctrval